Research and Development

The Medical School and Cancer Centre remit of the Human Genetics unit has been well supported by NHS Tayside over many years. In particular, translational cancer research and cutting edge cancer diagnostic services are a key Tayside strength, recognised at both Scottish and UK level. To this end the department has maintained a longstanding interest in Molecular Cytogenetic R&D, recently complimented by acquisition of high through-put Next Generation Sequencing (NGS) technology. As with previous developments (arrays, LCM, Pet-FISH) the aim is to incorporate these advances into new and improved diagnostic services.

The Department’s translational R&D efforts seek to add value to existing cancer research programmes within the Medical School ( breast, bowel, skin and kidney cancer) by utilising the same state-of-the-art equipment and clinical expertise as the diagnostic service. This includes a number of robotic systems, automated PET-FISH, Array-CGH and NGS. As with all successful clinical research this has involved a multidisciplinary partnership effort with other Medical School and University of Dundee colleagues. Each area of interest is underpinned by Grant funded research and oversight of dedicated clinical scientist. Students are co-supervised by senior NHS/University Staff and 3 PhD students have successfully completed their studies in recent years. We have been able to publish on a regular basis in good quality journals and present at appropriate National and International conferences. Most importantly, because our R&D effort is closely aligned to clinical need, this can quickly inform new or improved services to patients.